Dr. Gregory House: I created a case. I played nice because I was in a good mood. Because I didn't hurt.
Dr. Lisa Cuddy: You don't need your pain to be a good doctor.
Dr. Gregory House: I'm not interested in good.
Dr. Lisa Cuddy: You're afraid to be happy.
Dr. Gregory House: Why do you care if I'm happy?
Dr. Lisa Cuddy: [Long pause] You're afraid to change. The one thing you have is your intellect. You think if that's compromised, you have nothing.

[Offering House some methadone]

Dr. Lisa Cuddy: Just take it.
Dr. Gregory House: No.
Dr. Lisa Cuddy: Don't do this.
Dr. Gregory House: [Tosses the methadone in the trash]

It's already done. This is the only me you get.